Itakiso Jinja is a Shinto shrine located in Wakayama City, Wakayama Prefecture. The main deity of this shrine is Oyabiko no mikoto, son of Susano. Oyatsuhime no mikoto and Tsumahime no mikoto are also enshrined . They are younger sisters of Oyabiko no mikoto. Oyabiko and his younger sisters are enshrined as God of the tree. There is no knowledge of exactly when Itakiso Jinja was built, but it appeared in the Shoku Nihongi, an imperially commissioned Japanese history text in the early Heian Period.