Isonokami-jingu is a Shinto shrine located in Tenri City, Nara Prefecture, Japan. The Nihonshoki says the shrine dates back to the 7th century, when the Mononobe clan had military control over the area. The Mononobe clan was a powerful clan of the Kofun period and patronized the shrine for generations. It is said the shrine also served as an armory. This sacred shrine is dedicated to Futsunomitama no Okami.
It holds a number of national treasures and important cultural assets such as the seven-pronged sword, Nanasaya no Tachi. The ancient artifacts and treasures excavated in the shrine grounds in 1874 are enshrined in its main hall, built in 1913.